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Lexapro belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs), while Cymbalta belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs).īoth drug classes work by acting on the reuptake of certain neurotransmitters in the brain in order to elevate baseline levels of these neurotransmitters, which helps to improve and stabilize mood. Lexapro and Cymbalta belong to two different drug classes. We’ve put together a list of differences and similarities to help you understand how the medications compare. Lexapro, which is sold under the generic name escitalopram, and Cymbalta, which is sold under the generic name duloxetine, are both effective at treating mental health conditions like major depression and anxiety. With millions of Americans living with these conditions, antidepressant medications, which are often used for the treatment of depression and anxiety, are among the most commonly prescribed prescription drugs. Once you explain your concerns to your doctor, the two of you can discuss all the options and determine which one might be the best for you.Depression and anxiety disorders are two of the most common mental health conditions affecting adults in the United States. Never go off an antidepressant on your own without your doctor’s OK, because stopping too quickly can lead to a resurgence of symptoms and other side effects. Whether you’re currently dealing with antidepressant-induced sleep fallout, or you want help for your depression but would rather avoid sleep issues if possible, the first step is to talk to your doctor, Breus says.
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For example, a doctor may advise a patient to take a sedating antidepressant at nighttime. Vivid dreams may persist for some people, but lots of times, these sleep issues will subside after a couple of weeks, he adds. “Most people will tell you they mainly see when they first start, then it goes away,” Winter says. These sleep-related side effects often aren’t permanent. If you’re freaked out by how your antidepressant has affected your sleep (or how one might in the future), there’s some good news. Other types of antidepressants can bring about either fatigue or insomnia as side effects. That can result in feeling extra-energized, potentially causing insomnia, Breus says. On the other side of the spectrum, norepinephrine and dopamine reuptake inhibitors, like the popular drug bupropion (Wellbutrin), increase the levels of those two neurotransmitters in the brain. “When somebody is taking an SSRI, they have more serotonin in their system for longer, which can have a sedating effect,” leading to sleepiness. “Serotonin is a calming hormone,” Breus says. Take selective serotonin reuptake inhibitors (SSRIs), like sertraline (Zoloft) and paroxetine (Paxil). “All of these chemicals are big players in the pathways of maintaining or initiating sleep, or chemicals that help you feel awake during the day,” Winter says. These neurotransmitters play another role as well. Chris Winter, M.D., of Charlottesville Neurology and Sleep Medicine and author of The Sleep Solution, tells SELF. “Generally speaking, these medications affect neurotransmitters like serotonin, dopamine, and norepinephrine,” which are important for regulating your emotions, board-certified sleep medicine doctor and neurologist W.
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Although different people can react to the same medication in different ways, there are some basic rules for how various antidepressants might influence your sleep.